
GRF Analog
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
Tesamorelin is a synthetic analog of growth hormone-releasing factor (GRF) with a trans-3-hexenoyl group attached to the tyrosine at position 1. With the molecular formula C₂₂₁H₃₆₆N₇₂O₆₇S and a molecular weight of 5135.9 g/mol (CAS: 218949-48-5), Tesamorelin is a modified GRF analog with enhanced metabolic stability.
Y(3-hexenoyl)-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2Tesamorelin binds to GHRH receptors with enhanced affinity due to hexenoyl modification, activating Gs-protein signaling (PMID: 19928588).
Scientific Context