What is Thymosin Alpha-1 used for?

Thymosin Alpha-1 is a synthetic peptide compound studied in laboratory research settings. Scientific literature has explored its properties in preclinical studies. It is not approved for human consumption.

What purity level does Onward Aminos's Thymosin Alpha-1 have?

Onward Aminos supplies Thymosin Alpha-1 at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is Thymosin Alpha-1 supplied?

Thymosin Alpha-1 is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

FREE SHIPPING THRESHOLD$250 REMAINING

SYSTEM: ACTIVE·INVENTORY // PEPTIDES·ITEM: THYMOSIN ALPHA-1

MK-IV SPEC Thymosin Alpha-1

LAT: 34.0522° NLONG: 118.2437° W

RESEARCH ONLYOA-1129-THYALP

Thymosin Alpha-1

Name: Thymosin Alpha-1
Brand: Onward Aminos
SKU: OA-THYMOSINALPHA1

Thymic Peptide

UNIT COST$56.00

STATUSIN STOCK

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MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.

SPECIFICATIONS

CAS No.62304-98-7

Mol. Weight3108.35 g/mol

Purity≥99.0% (HPLC)

FormLyophilized Powder

Storage−20°C · Lyophilized

Mol. FormulaC₁₂₉H₂₁₅N₃₃O₅₅

COMPOUND INTEL

REF #OA-1129-THYALP

MECHANISM_DUMP

MOLECULAR PROFILE

Thymosin Alpha-1 is a synthetic version of a naturally occurring thymic peptide originally isolated from thymosin fraction 5. With the molecular formula C₁₂₉H₂₁₅N₃₃O₅₅ and a molecular weight of 3108.3 g/mol (CAS: 62304-98-7), Thymosin Alpha-1 is a 28-amino acid peptide representing the N-terminal acetylated fragment of prothymosin alpha.

AMINO ACID SEQUENCEAc-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn

Thymic PeptideTLR ReceptorsT-Cell Receptors

MECHANISM OF ACTION

TLR SignalingMyD88-dependent pathway

Thymosin Alpha-1 interacts with Toll-like receptors, activating MyD88-dependent signaling and NF-κB translocation in immune cell cultures (PMID: 16683274).

T-Cell ActivationTCR signaling enhancement

Research indicates the peptide enhances T-cell receptor signaling and T-cell differentiation markers in lymphocyte cultures (PMID: 18423086).

TECHNICAL DATA

CAS No.: 62304-98-7
Mol. Formula: C₁₂₉H₂₁₅N₃₃O₅₅
Mol. Weight: 3108.35 g/mol
Purity: ≥99.0% (HPLC)
Form: Lyophilized Powder
Storage: −20°C · Lyophilized

PMID REFERENCE LIBRARY

PMID: 16683274

Romani et al. (2006) characterized Thymosin Alpha-1's interactions with Toll-like receptors and dendritic cell activation markers in vitro (PMID: 16683274).

Romani L, et al. (2006). Thymosin alpha1 and immune response. Immunol Today.PMID: 18423086

King et al. (2008) reviewed Thymosin Alpha-1's receptor binding properties and intracellular signaling pathways in immune cell models (PMID: 18423086).

King R, et al. (2008). Thymosin alpha1: molecular mechanisms. Expert Opin Biol Ther.