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MK-IV SPEC
LAT: 34.0522° NLONG: 118.2437° W
RESEARCH ONLYOA-905-ARA290
ARA-290
Helix B Surface Peptide (Hbsp)
UNIT COST$96.00
STATUSIN STOCK
QTY
1
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
SPECIFICATIONS
CAS No.1208243-50-8
Mol. Weight1257.3 g/mol
Purity≥99.0% (HPLC)
FormLyophilized Powder
Storage−20°C · Lyophilized
Mol. FormulaC51H84N16O21
COMPOUND INTEL
REF #OA-905-ARA290MECHANISM_DUMP
MOLECULAR PROFILE
Ara-290 is a Helix B surface peptide (HBSP) and 11-amino acid non-erythropoietic EPO analog. With the molecular formula C₅₁H₈₄N₁₆O₂₁ and a molecular weight of 1256.4 g/mol (CAS: 1208243-50-8), it structurally mimics endogenous peptides while extending its sequence.
AMINO ACID SEQUENCE
Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-SerHelix B Surface Peptide (Hbsp)Innate Repair Receptor (IRR)Erythropoietin Receptor Heterodimer
MECHANISM OF ACTION
Innate Repair Receptor (IRR)Receptor interaction
Published research demonstrates Ara-290 modulates targeted signaling cascades within cell tissue models (PMID: 32345869).
Erythropoietin Receptor HeterodimerSignaling cascade
In cellular environments, Ara-290 exhibits selective binding and corresponding pathway activation (PMID: 32335150).
TECHNICAL DATA
- CAS No.
- 1208243-50-8
- Mol. Formula
- C51H84N16O21
- Mol. Weight
- 1257.3 g/mol
- Purity
- ≥99.0% (HPLC)
- Form
- Lyophilized Powder
- Storage
- −20°C · Lyophilized
PMID REFERENCE LIBRARY
PMID: 32345869
Yao et al. (2020) investigated Ara-290's binding affinity and receptor interactions in vitro (PMID: 32345869).
Yao M, et al. (2020). Improvement of Islet Allograft Function Using Cibinetide, an Innate Repair Receptor Ligand. Transplantation.PMID: 32335150Shokrzadeh et al. (2020) investigated Ara-290's binding affinity and receptor interactions in vitro (PMID: 32335150).
Shokrzadeh M, et al. (2020). An engineered non-erythropoietic erythropoietin-derived peptide, ARA290, attenuates doxorubicin induced genotoxicity and oxidative stress. Toxicol In Vitro.
