What is Selank used for?

Selank is a synthetic peptide compound studied in laboratory research settings. Scientific literature has explored its properties in preclinical studies. It is not approved for human consumption.

What purity level does Onward Aminos's Selank have?

Onward Aminos supplies Selank at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is Selank supplied?

Selank is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

FREE SHIPPING THRESHOLD$250 REMAINING

SYSTEM: ACTIVE·INVENTORY // PEPTIDES·ITEM: SELANK

MK-IV SPEC Selank

LAT: 34.0522° NLONG: 118.2437° W

RESEARCH ONLYOA-1091-SEL

Selank

Name: Selank
Brand: Onward Aminos
SKU: OA-SELANK

Tuftsin Analog

UNIT COST$26.00

STATUSIN STOCK

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MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.

SPECIFICATIONS

CAS No.129954-34-3

Mol. Weight751.86 g/mol

Purity≥99.0% (HPLC)

FormLyophilized Powder

Storage−20°C · Lyophilized

Mol. FormulaC₃₃H₅₇N₉O₁₅

COMPOUND INTEL

REF #OA-1091-SEL

MECHANISM_DUMP

MOLECULAR PROFILE

Selank is a synthetic heptapeptide analog of the endogenous tuftsin peptide with an added glycine-proline-lysine (Gly-Pro-Lys) sequence at the C-terminus. With the molecular formula C₄₆H₇₃N₁₃O₁₃ and a molecular weight of 1046.2 g/mol (CAS: 129954-34-3), Selank consists of seven amino acids: Thr-Lys-Pro-Arg-Pro-Gly-Pro.

AMINO ACID SEQUENCEThr-Lys-Pro-Arg-Pro-Gly-Pro

Tuftsin AnalogGABA-A ReceptorsInterleukin-6 Pathway

MECHANISM OF ACTION

GABA-A ReceptorAllosteric modulation

Selank binds to GABA-A receptors as an allosteric modulator, affecting receptor subunit composition and chloride channel conductance (PMID: 22786332).

Cytokine ExpressionIL-6 modulation

Published research indicates Selank influences interleukin-6 expression and other inflammatory mediators in glial cell cultures (PMID: 22968004).

TECHNICAL DATA

CAS No.: 129954-34-3
Mol. Formula: C₃₃H₅₇N₉O₁₅
Mol. Weight: 751.86 g/mol
Purity: ≥99.0% (HPLC)
Form: Lyophilized Powder
Storage: −20°C · Lyophilized

PMID REFERENCE LIBRARY

PMID: 22786332

Kozlovskaya et al. (2012) characterized Selank's binding to GABA-A receptors and its allosteric modulation properties in neuronal cell cultures (PMID: 22786332).

Kozlovskaya MM, et al. (2012). Selank and GABA receptors. Bull Exp Biol Med.PMID: 22968004

Kozlovsky et al. (2012) investigated Selank's effects on neurotransmitter systems and cytokine expression in brain tissue models (PMID: 22968004).

Kozlovsky VI, et al. (2012). Selank: mechanism of action. Rev Neurosci.PMID: 20717095

Uchakina et al. (2010) examined Selank's immunomodulatory properties and interleukin expression in immune cell cultures (PMID: 20717095).

Uchakina ON, et al. (2010). Immunomodulatory effects of Selank. Bull Exp Biol Med.