Skip to main contentFREE SHIPPING THRESHOLD$250 REMAINING
MK-IV SPEC
LAT: 34.0522° NLONG: 118.2437° W
RESEARCH ONLYOA-949-EPI
Epitalon
Tetrapeptide
UNIT COST$46.00
STATUSIN STOCK
SELECT MASS (MG)
QTY
1
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
SPECIFICATIONS
CAS No.307297-39-8
Mol. Weight390.35 g/mol
Purity≥99.0% (HPLC)
FormLyophilized Powder
Storage−20°C · Lyophilized
Mol. FormulaC14H22N4O9
COMPOUND INTEL
REF #OA-949-EPIMECHANISM_DUMP
MOLECULAR PROFILE
Epitalon (also known as Epithalon or Epithalamin) is a synthetic tetrapeptide derived from the pineal gland peptide Epithalamin. With the molecular formula C₁₄H₂₂N₄O₉ and a molecular weight of 390.4 g/mol (CAS: 76066-85-2), Epitalon consists of four amino acids (Ala-Glu-Asp-Gly) and mimics the endogenous peptide involved in melatonin regulation.
AMINO ACID SEQUENCE
Ala-Glu-Asp-GlyTetrapeptideTelomerase ComplexTRH Receptors
MECHANISM OF ACTION
Telomerase ActivityhTERT gene expression
Epitalon has been shown to increase telomerase activity and elongate telomeres in human somatic cell cultures through hTERT upregulation (PMID: 19619679).
Melatonin SynthesisArylalkylamine N-acetyltransferase
Research indicates Epitalon influences melatonin-producing enzyme expression in pineal gland cell models (PMID: 26637836).
TECHNICAL DATA
- CAS No.
- 307297-39-8
- Mol. Formula
- C14H22N4O9
- Mol. Weight
- 390.35 g/mol
- Purity
- ≥99.0% (HPLC)
- Form
- Lyophilized Powder
- Storage
- −20°C · Lyophilized
PMID REFERENCE LIBRARY
PMID: 19619679
Khavinson et al. (2009) investigated Epitalon's effects on telomerase activity and gene expression in human somatic cell cultures (PMID: 19619679).
Khavinson VKh, et al. (2009). Epitalon and telomerase activity. Bull Exp Biol Med.PMID: 14696864Khavinson et al. (2003) characterized Epitalon's molecular structure and its interactions with pineal gland function in vitro (PMID: 14696864).
Khavinson VKh, et al. (2003). Peptide regulation of aging. Neuro Endocrinol Lett.PMID: 26637836Korkushko et al. (2015) examined Epitalon's mechanism of action on melatonin synthesis enzymes in pinealocyte cultures (PMID: 26637836).
Korkushko OV, et al. (2015). Epitalon and pineal gland peptides. Adv Gerontol.
Scientific Context