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MK-IV SPEC
LAT: 34.0522° NLONG: 118.2437° W
RESEARCH ONLYOA-1035-KPV
KPV
C-Terminal Tripeptide
UNIT COST$34.00
STATUSIN STOCK
SELECT MASS (MG)
QTY
1
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
SPECIFICATIONS
CAS No.67727-97-3
Mol. Weight342.43 g/mol
Purity≥99.0% (HPLC)
FormLyophilized Powder
Storage−20°C · Lyophilized
Mol. FormulaC16H30N4O4
COMPOUND INTEL
REF #OA-1035-KPVMECHANISM_DUMP
MOLECULAR PROFILE
KPV is a C-terminal tripeptide of alpha-MSH (Lys-Pro-Val) and anti-inflammatory peptide. With the molecular formula C₁₈H₃₃N₅O₄ and a molecular weight of 383.5 g/mol (CAS: 17750-43-5), it presents a well-characterized amino acid structure.
AMINO ACID SEQUENCE
Lys-Pro-ValC-Terminal TripeptideNF-κB PathwayIntestinal epithelial signaling
MECHANISM OF ACTION
NF-κB PathwayReceptor interaction
Published research demonstrates KPV modulates targeted signaling cascades within cell tissue models (PMID: 39252648).
Intestinal epithelial signalingSignaling cascade
In cellular environments, KPV exhibits selective binding and corresponding pathway activation (PMID: 30661264).
TECHNICAL DATA
- CAS No.
- 67727-97-3
- Mol. Formula
- C16H30N4O4
- Mol. Weight
- 342.43 g/mol
- Purity
- ≥99.0% (HPLC)
- Form
- Lyophilized Powder
- Storage
- −20°C · Lyophilized
PMID REFERENCE LIBRARY
PMID: 39252648
Zhang et al. (2024) investigated KPV's binding affinity and receptor interactions in vitro (PMID: 39252648).
Zhang L, et al. (2024). KPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy. Adv Healthc Mater.PMID: 30661264Böhm et al. (2019) investigated KPV's binding affinity and receptor interactions in vitro (PMID: 30661264).
Böhm M, et al. (2019). Are melanocortin peptides future therapeutics for cutaneous wound healing? Exp Dermatol.
