What is Semax used for?

Semax is a synthetic peptide compound studied in laboratory research settings. Scientific literature has explored its properties in preclinical studies. It is not approved for human consumption.

What purity level does Onward Aminos's Semax have?

Onward Aminos supplies Semax at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is Semax supplied?

Semax is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

FREE SHIPPING THRESHOLD$250 REMAINING

SYSTEM: ACTIVE·INVENTORY // PEPTIDES·ITEM: SEMAX

MK-IV SPEC Semax

LAT: 34.0522° NLONG: 118.2437° W

RESEARCH ONLYOA-1097-SEM

Semax

Name: Semax
Brand: Onward Aminos
SKU: OA-SEMAX

ACTH Fragment Analog

UNIT COST$29.00

STATUSIN STOCK

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MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.

SPECIFICATIONS

CAS No.80714-61-0

Mol. Weight813.93 g/mol

Purity≥99.0% (HPLC)

FormLyophilized Powder

Storage−20°C · Lyophilized

Mol. FormulaC₃₇H₅₁N₉O₁₀S

COMPOUND INTEL

REF #OA-1097-SEM

MECHANISM_DUMP

MOLECULAR PROFILE

Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment 4-10 with modifications. With the molecular formula C₃₇H₅₁N₉O₁₀ and a molecular weight of 812.9 g/mol (CAS: 80714-61-0), Semax consists of the sequence Met-Glu-His-Phe-Pro-Gly-Pro with an N-terminal proline and C-terminal glycine-proline added.

AMINO ACID SEQUENCEPro-Gly-Pro-Glu-His-Phe-Met

ACTH Fragment AnalogBDNF/TrkB PathwayNeurotrophic Factors

MECHANISM OF ACTION

BDNF/TrkB SignalingNeurotrophin receptor activation

Semax increases brain-derived neurotrophic factor expression and activates TrkB receptors in neuronal cultures (PMID: 16445185).

Gene ExpressionTranscriptional regulation

Research demonstrates Semax modulates expression of genes involved in neuroplasticity and neurotrophic factor production (PMID: 18841466).

TECHNICAL DATA

CAS No.: 80714-61-0
Mol. Formula: C₃₇H₅₁N₉O₁₀S
Mol. Weight: 813.93 g/mol
Purity: ≥99.0% (HPLC)
Form: Lyophilized Powder
Storage: −20°C · Lyophilized

PMID REFERENCE LIBRARY

PMID: 16445185

Ashmarin et al. (2006) investigated Semax's effects on BDNF expression and TrkB receptor activation in neuronal cell cultures (PMID: 16445185).

Ashmarin IP, et al. (2006). Semax and brain-derived neurotrophic factor. Zh Vyssh Nerv Deiat.PMID: 18841466

Medvedeva et al. (2008) characterized Semax's effects on gene expression profiles and neurotrophic factor production in brain tissue models (PMID: 18841466).

Medvedeva EV, et al. (2008). Semax: molecular mechanisms. Ross Fiziol Zh.