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MK-IV SPEC
LAT: 34.0522° NLONG: 118.2437° W
RESEARCH ONLYOA-1067-NAD
NAD+
Dinucleotide Coenzyme
UNIT COST$68.00
STATUSIN STOCK
SELECT MASS (MG)
QTY
1
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
SPECIFICATIONS
CAS No.53-84-9
Mol. Weight663.43 g/mol (anhydrous free acid)
Purity≥99.0% (HPLC)
FormLyophilized Powder
Storage−20°C · Lyophilized
Mol. FormulaC21H27N7O14P2
COMPOUND INTEL
REF #OA-1067-NADMECHANISM_DUMP
MOLECULAR PROFILE
NAD+ (Nicotinamide Adenine Dinucleotide) is a dinucleotide coenzyme composed of nicotinamide and adenine connected via phosphate groups. With the molecular formula C₂₁H₂₇N₇O₁₄P₂ and a molecular weight of 663.4 g/mol (CAS: 53-84-9), NAD+ is an essential electron carrier in cellular metabolism.
AMINO ACID SEQUENCE
N/A (Non-peptide compound)Dinucleotide CoenzymeSirtuins (SIRT1-7)PARP Enzymes
MECHANISM OF ACTION
SirtuinsNAD+-dependent deacetylation
NAD+ serves as a coenzyme for sirtuin deacetylases, regulating protein acetylation status in metabolic pathways (PMID: 23295476).
Cellular EnergyRedox reactions
As a redox cofactor, NAD+ cycles between oxidized and reduced states in glycolysis, TCA cycle, and oxidative phosphorylation (PMID: 29388144).
TECHNICAL DATA
- CAS No.
- 53-84-9
- Mol. Formula
- C21H27N7O14P2
- Mol. Weight
- 663.43 g/mol (anhydrous free acid)
- Purity
- ≥99.0% (HPLC)
- Form
- Lyophilized Powder
- Storage
- −20°C · Lyophilized
PMID REFERENCE LIBRARY
PMID: 23295476
Imai et al. (2013) characterized NAD+ as a substrate for sirtuin deacetylases and its role in metabolic regulation in vitro (PMID: 23295476).
Imai S, et al. (2013). NAD+ and sirtuins. Trends Cell Biol.PMID: 29388144Rajman et al. (2018) reviewed NAD+-dependent enzymatic pathways including sirtuins, PARPs, and CD38 in cellular models (PMID: 29388144).
Rajman L, et al. (2018). NAD+ metabolism and cellular health. Cell Metab.
