
Amp-Kinase Activator
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
AICAR is a AMP-kinase activator and nucleoside analog. With the molecular formula C₉H₁₄N₄O₅ and a molecular weight of 258.24 g/mol (CAS: 2627-69-2), it is characterized in foundational biochemical research.
Published research demonstrates AICAR modulates targeted signaling cascades within cell tissue models (PMID: 41764514).
In cellular environments, AICAR exhibits selective binding and corresponding pathway activation (PMID: 41719297).
Tian et al. (2026) investigated AICAR's binding affinity and receptor interactions in vitro (PMID: 41764514).
Tian YY, et al. (2026). A novel Chinese medicine formula against hyperuricemia-induced kidney inflammation involving pyroptosis inhibition via modulating AMPK-TLR4-NLRP3 pathway. Chin Med.PMID: 41719297Fu et al. (2026) investigated AICAR's binding affinity and receptor interactions in vitro (PMID: 41719297).
Fu W, et al. (2026). FNDC5/Irisin-dependent renoprotection of resistance training in myocardial infarction-induced Type 2 cardiorenal syndrome. PLoS One.