What is Melanotan 2 used for?

Melanotan 2 is a synthetic peptide compound studied in laboratory research settings. Scientific literature has explored its properties in preclinical studies. It is not approved for human consumption.

What purity level does Onward Aminos's Melanotan 2 have?

Onward Aminos supplies Melanotan 2 at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is Melanotan 2 supplied?

Melanotan 2 is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

FREE SHIPPING THRESHOLD$250 REMAINING

SYSTEM: ACTIVE·INVENTORY // PEPTIDES·ITEM: MELANOTAN 2

MK-IV SPEC Melanotan 2

LAT: 34.0522° NLONG: 118.2437° W

RESEARCH ONLYOA-1063-MEL2

Melanotan 2

Name: Melanotan 2
Brand: Onward Aminos
SKU: OA-MELANOTAN2

Cyclic Melanocortin Analog

UNIT COST$29.00

STATUSIN STOCK

Backorder · Ships in 14–21 days

QTY

MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.

SPECIFICATIONS

CAS No.121062-08-6

Mol. Weight1024.18 g/mol (free base)

Purity≥99.0% (HPLC)

FormLyophilized Powder

Storage−20°C · Lyophilized

Mol. FormulaC₅₀H₆₉N₁₅O₉

COMPOUND INTEL

REF #OA-1063-MEL2

MECHANISM_DUMP

MOLECULAR PROFILE

Melanotan 2 (MT-II) is a cyclic heptapeptide melanocortin analog with the molecular formula C₅₀H₆₉N₁₅O₉ and a molecular weight of 1024.18 g/mol (CAS: 121062-08-6), a synthetic analog of alpha-melanocyte-stimulating hormone (α-MSH) studied in melanocortin receptor binding assays and pigmentation cell models. Supplied at ≥99% HPLC purity as a lyophilized powder, Melanotan 2 is designated for in vitro research on melanocortin receptor pharmacology only.

AMINO ACID SEQUENCEAc-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2

Cyclic Melanocortin AnalogMC1R (Melanocortin 1 Receptor)MC3RMC4RMC5R

MECHANISM OF ACTION

MC1R/MC4RcAMP/PKA signaling

Melanotan 2 binds melanocortin receptors and activates adenylyl cyclase, stimulating cAMP accumulation in melanocyte and hypothalamic cell models (PMID: 7682608).

Melanogenesis PathwayTyrosinase activation

MC1R-mediated cAMP elevation activates MITF transcription factor and downstream tyrosinase expression in melanocyte cell culture models (PMID: 8455727).

TECHNICAL DATA

CAS No.: 121062-08-6
Mol. Formula: C₅₀H₆₉N₁₅O₉
Mol. Weight: 1024.18 g/mol (free base)
Purity: ≥99.0% (HPLC)
Form: Lyophilized Powder
Storage: −20°C · Lyophilized

PMID REFERENCE LIBRARY

PMID: 7682608

Dorr et al. (1993) characterized Melanotan 2's binding affinity and selectivity across melanocortin receptor subtypes in cell-based binding assays (PMID: 7682608).

Dorr RT, et al. (1993). Melanocyte-stimulating hormone analogs: in vitro and in vivo potency. Life Sci.PMID: 8455727

Hadley et al. (1993) analyzed cAMP signaling downstream of MC1R and MC4R activation by synthetic alpha-MSH analogs in melanocyte cultures (PMID: 8455727).

Hadley ME, et al. (1993). Melanocyte stimulating hormone (MSH) receptors. Regul Pept.