
Dual Glp-1/Glucagon
MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.
Mazdutide is a dual GLP-1/glucagon receptor agonist with a lipid side chain. With the molecular formula C₂₀₅H₃₁₅N₅₁O₆₆ and a molecular weight of 4525.0 g/mol (CAS: 2496030-49-4), it presents a well-characterized amino acid structure.
Ac-[D-Ala2]-GLP-1/Glucagon chimeric analoguePublished research demonstrates Mazdutide modulates targeted signaling cascades within cell tissue models (PMID: 41804840).
In cellular environments, Mazdutide exhibits selective binding and corresponding pathway activation (PMID: 41787737).
Azam et al. (2026) investigated Mazdutide's binding affinity and receptor interactions in vitro (PMID: 41804840).
Azam MH, et al. (2026). Efficacy and Safety of Mazdutide in Managing Overweight and Obesity Among Non-Diabetic Adults: A Meta-Analysis of Randomised Controlled Trials. Diabetes Obes Metab.PMID: 41787737Abulehia et al. (2026) investigated Mazdutide's binding affinity and receptor interactions in vitro (PMID: 41787737).
Abulehia A, et al. (2026). Comparative Efficacy and Safety of Glucagon Receptor Agonists on Metabolic Outcomes: A Network Meta-Analysis of Randomised Controlled Trials. Endocrinol Diabetes Metab.