What is GLP-1(S) used for?

GLP-1(S) is a synthetic peptide compound studied in laboratory research settings. Scientific literature has explored its properties in preclinical studies. It is not approved for human consumption.

What purity level does Onward Aminos's GLP-1(S) have?

Onward Aminos supplies GLP-1(S) at ≥99% purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is GLP-1(S) supplied?

GLP-1(S) is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

FREE SHIPPING THRESHOLD$250 REMAINING

SYSTEM: ACTIVE·INVENTORY // PEPTIDES·ITEM: GLP-1(S)

MK-IV SPEC GLP-1(S)

LAT: 34.0522° NLONG: 118.2437° W

RESEARCH ONLYOA-977-GLP1S

GLP-1(S)

Name: GLP-1(S)
Brand: Onward Aminos
SKU: OA-GLP1S

GLP-1 Receptor Agonist Analog

UNIT COST$51.00

STATUSIN STOCK

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MISSION CRITICAL: For in vitro laboratory research only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+.

SPECIFICATIONS

CAS No.910463-68-2

Mol. Weight4113.58 g/mol

Purity≥99.0% (HPLC)

FormLyophilized Powder

Storage−20°C · Lyophilized

Mol. FormulaC₁₈₇H₂₉₁N₄₅O₅₉

COMPOUND INTEL

REF #OA-977-GLP1S

MECHANISM_DUMP

MOLECULAR PROFILE

GLP-1(S) is a semaglutide-class GLP-1 receptor agonist research peptide with the molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and a molecular weight of 4113.58 g/mol (CAS: 910463-68-2), characterized by a C18 fatty diacid side chain enabling albumin binding and extended plasma half-life in preclinical pharmacokinetic studies. Supplied at ≥99% HPLC purity as a lyophilized powder, GLP-1(S) is designated for in vitro research on GLP-1 receptor signaling pathways only.

GLP-1 Receptor Agonist AnalogGLP-1 Receptor (GLP-1R)cAMP/PKA PathwayInsulin Secretion Cascade

MECHANISM OF ACTION

GLP-1 ReceptorcAMP/PKA activation

GLP-1(S) binds GLP-1R and activates adenylyl cyclase, elevating intracellular cAMP in pancreatic and intestinal cell models (PMID: 28890133).

Albumin BindingExtended half-life via fatty acid chain

The C18 fatty diacid side chain enables non-covalent albumin binding, extending pharmacokinetic half-life in plasma protein binding assays (PMID: 29393665).